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Cruise sailings to Santiago, Chile

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Showing 1–30 of 80 sailings

Seabourn Pursuit · South America

10-Day Chilean Fjords

Nov 12 to Nov 22, 2026 · 10 nights

San Antonio (Santiago), Chile to Buenos Aires

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Explore Beyond Event, The Finale Sail

Ports of call and details

From $5,939 per guest based on double occupancy

Veranda Suite, The Finale Sail

Taxes & fees included

Veranda Suite
$5,939
Penthouse Suite
$12,998
Panorama Penthouse Suite
$13,908
Ocean View
Owner's Suite and Above
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Majestic Princess · South America

Brazilian & Cape Horn Grand Adventure

Nov 19 to Dec 22, 2026 · 33 nights

Ft. Lauderdale, Florida to Santiago (Valparaiso), Chile

  • 3rd and 4th guests sail free

Offers: Last Minute Cruise Deals

Ports of call and details

Save $4,171 · 60% off

From $2,788$6,959 per person, double occupancy

Interior, Last Minute Cruise Deals

+ $883 taxes & fees

Interior
$2,788$6,959
Balcony
$3,856$10,919
Mini-Suite
$4,588$12,539
Suite
$12,148$20,909
Oceanview
Request this sailing

Majestic Princess · South America

Cape Horn & Glaciers of Patagonia

Dec 7 to Dec 22, 2026 · 15 nights

Buenos Aires, Argentina to Santiago (Valparaiso), Chile

  • 3rd and 4th guests sail free

Offers: Last Minute Cruise Deals

Ports of call and details

Save $2,525 · 57% off

From $1,884$4,409 per person, double occupancy

Interior, Last Minute Cruise Deals

+ $673 taxes & fees

Interior
$1,884$4,409
Mini-Suite
$2,069$7,609
Balcony
$2,091$6,729
Suite
$7,999$13,049
Oceanview
Request this sailing

Majestic Princess · South America

Cape Horn & Glaciers of Patagonia

Dec 22, 2026 to Jan 6, 2027 · 15 nights

Santiago (Valparaiso), Chile to Buenos Aires, Argentina

Offers: Last Minute Cruise Deals

Ports of call and details

Save $3,183 · 63% off

From $1,906$5,089 per person, double occupancy

Interior, Last Minute Cruise Deals

+ $553 taxes & fees

Interior
$1,906$5,089
Balcony
$2,102$7,269
Mini-Suite
$2,199$8,209
Suite
$8,107$14,199
Oceanview
Request this sailing

Oceania CruisesOceania Insignia · South America

Patagonian Panorama: Lima to Buenos Aires

Jan 3 to Jan 24, 2027 · 21 nights

Lima/Machu Picchu (Callao), Peru to Buenos Aires, Argentina

  • Specialty coffees, sodas, juices and water
  • Wi-Fi throughout the ship
  • Shipboard gratuities included
  • Specialty restaurants included
  • +1 more

Offers: Your World Included

Ports of call and details

Save $7,899 · 50% off

From $7,899$15,798 per guest, double occupancy; air not included

Inside Stateroom (G)

Inside Stateroom (G)
$7,899$15,798
Ocean View
$8,349$16,698
Deluxe Ocean View (C2)
$8,849$17,698
Deluxe Ocean View (C1)
$9,049$18,098
Veranda Stateroom (B2)
$13,099$26,198
Veranda Stateroom (B1)
$13,449$26,898
Inside Stateroom (F)
Concierge Level Veranda (A1)
Concierge Level Veranda (A2)
Concierge Level Veranda (A3)
Penthouse Suite (PH1)
Penthouse Suite (PH2)
Penthouse Suite (PH3)
Owner’s Suite
Vista Suite
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Queen Anne · South America

Fort Lauderdale

Jan 22 to Mar 19, 2027 · 56 nights

Round trip from Fort Lauderdale, Florida, USA

  • Up to $200 onboard credit per stateroom
  • Reduced refundable deposit

Offers: Sailing Soon Savings, 2026 Black Friday Event

Ports of call and details

From $7,999 per person, double occupancy

Britannia Inside

Taxes & fees included

Britannia Inside
$7,999
Britannia Oceanview
$11,999
Britannia Balcony
$12,999
Britannia Club Balcony
$16,099
Princess Grill Suite
$22,899
Queens Grill Suite
$55,899
Request this sailing

Oosterdam · South America

22-Day South America & Antarctica

Feb 1 to Feb 23, 2027 · 22 nights

Buenos Aires, Argentina to San Antonio (Santiago), Chile

  • Drink package
  • Wi-Fi
  • Specialty dining
  • Shore excursions

Offers: Have It All - Our Premium Cruise Package

Ports of call and details

From $6,999 per person, double occupancy

Inside, Have It All - Our Premium Cruise Package

Taxes & fees included

Inside
$6,999
Ocean View
$7,099
Verandah
$9,299
Signature Suite
$11,299
Neptune Suite
$14,599
Request this sailing

Queen Anne · South America

20 nights - Rio de Janiero to Valparaiso - February 2027

Feb 8 to Feb 28, 2027 · 20 nights

Rio de Janeiro, Brazil to Valparaiso (tours to Santiago), Chile

  • Reduced refundable deposit

Offers: Sailing Soon Savings, Fall Savings Event

Ports of call and details

From $3,799 per person, double occupancy

Britannia Inside

Taxes & fees included

Britannia Inside
$3,799
Britannia Oceanview
$5,499
Britannia Balcony
$6,099
Britannia Club Balcony
$7,599
Princess Grill Suite
$11,549
Queens Grill Suite
$19,649
Request this sailing

Regent Seven Seas CruisesSeven Seas Mariner · South America

Antarctic Encounter: Buenos Aires to Lima (Callao)

Feb 20 to Mar 10, 2027 · 18 nights

Buenos Aires, Argentina to Lima, Perú

  • Unlimited beverages, fine wines and cocktails
  • Unlimited Wi-Fi
  • Pre-paid gratuities
  • All specialty restaurants included
  • +1 more

Offers: Bonus Savings of up to $3,700 per person

Ports of call and details

Save $22,499 · 60% off

From $15,099$37,598 per person, double occupancy, all-inclusive fare; air not included

Deluxe Veranda Suite G

Deluxe Veranda Suite G
$15,099$37,598
Deluxe Veranda Suite F
$15,199$37,798
Concierge Suite E
$15,599$38,598
Concierge Suite D
$16,099$39,598
Penthouse Suite C
$22,649$52,698
Penthouse Suite B
$22,749$52,898
Penthouse Suite A
$22,849$53,098
Seven Seas Suite Aft
$33,949$75,298
Seven Seas Suite Forward
$33,949$75,298
Mariner Suite MN
$41,149$89,698
Signature Suite SG
$58,549$124,498
Deluxe Veranda Suite H
Horizon View Suite HS
Grand Suite GS
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Oosterdam · South America

14-Day South America Pathways: Chilean Fjords & Glaciers

Feb 23 to Mar 9, 2027 · 14 nights

San Antonio (Santiago), Chile to Buenos Aires, Argentina

  • Drink package
  • Wi-Fi
  • Specialty dining
  • Shore excursions

Offers: Have It All - Our Premium Cruise Package

Ports of call and details

From $3,649 per person, double occupancy

Inside, Have It All - Our Premium Cruise Package

Taxes & fees included

Inside
$3,649
Ocean View
$3,749
Verandah
$5,299
Request this sailing

Queen Anne · South America

Valparaiso To Fort Lauderdale

Feb 28 to Mar 19, 2027 · 19 nights

Valparaiso (tours to Santiago), Chile to Fort Lauderdale, Florida, USA

  • Up to $200 onboard credit per stateroom
  • Reduced refundable deposit

Offers: Fall Savings Event, 2026 Black Friday Event

Ports of call and details

From $2,699 per person, double occupancy

Britannia Inside

Taxes & fees included

Britannia Inside
$2,699
Britannia Oceanview
$3,539
Britannia Balcony
$3,799
Britannia Club Balcony
$6,039
Princess Grill Suite
$8,999
Queens Grill Suite
$16,559
Request this sailing

Queen Anne · South America

Valparaiso To Southampton

Feb 28 to Apr 2, 2027 · 33 nights

Valparaiso (tours to Santiago), Chile to Southampton, England

  • Up to $200 onboard credit per stateroom
  • Reduced refundable deposit

Offers: Sailing Soon Savings, Fall Savings Event, 2026 Black Friday Event

Ports of call and details

From $4,349 per person, double occupancy

Britannia Inside

Taxes & fees included

Britannia Inside
$4,349
Britannia Oceanview
$6,489
Britannia Balcony
$6,789
Britannia Club Balcony
$9,669
Princess Grill Suite
$15,969
Queens Grill Suite
$23,349
Request this sailing

Queen Anne · South America

Valparaiso To Hamburg

Feb 28 to Apr 5, 2027 · 36 nights

Valparaiso (tours to Santiago), Chile to Hamburg, Germany

  • Up to $200 onboard credit per stateroom
  • Reduced refundable deposit

Offers: Fall Savings Event, 2026 Black Friday Event

Ports of call and details

From $5,299 per person, double occupancy

Britannia Inside

Taxes & fees included

Britannia Inside
$5,299
Britannia Oceanview
$7,329
Britannia Balcony
$7,989
Britannia Club Balcony
$10,749
Princess Grill Suite
$17,799
Queens Grill Suite
$25,089
Request this sailing

Oosterdam · South America

15-Day South America Pathways: Chilean Fjords & Glaciers

Mar 9 to Mar 24, 2027 · 15 nights

Buenos Aires, Argentina to San Antonio (Santiago), Chile

  • Drink package
  • Wi-Fi
  • Specialty dining
  • Shore excursions

Offers: Have It All - Our Premium Cruise Package

Ports of call and details

From $3,749 per person, double occupancy

Inside, Have It All - Our Premium Cruise Package

Taxes & fees included

Inside
$3,749
Ocean View
$3,949
Verandah
$5,699
Neptune Suite
$14,909
Request this sailing

Seabourn Pursuit · South America

25-Day White Continent & Chilean Fjords Explorer

Mar 13 to Apr 7, 2027 · 25 nights

Buenos Aires, Argentina to San Antonio (Santiago), Chile

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $28,798 per guest based on double occupancy

Veranda Suite, Seabourn Combo Savings

Taxes & fees included

Veranda Suite
$28,798
Penthouse Suite
$36,898
Panorama Penthouse Suite
$39,483
Owner's Suite and Above
Request this sailing

Seabourn Pursuit · South America

44-Day Antarctica, Chilean Fjords, Easter & Pitcairn Islands

Mar 13 to Apr 26, 2027 · 44 nights

Buenos Aires, Argentina to Papeete, French Polynesia

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $44,298 per guest based on double occupancy

Veranda Suite, Seabourn Combo Savings

Taxes & fees included

Veranda Suite
$44,298
Penthouse Suite
Panorama Penthouse Suite
Owner's Suite and Above
Request this sailing

Seabourn Pursuit · South America

15-Day Chilean Fjords Explorer

Mar 23 to Apr 7, 2027 · 15 nights

Buenos Aires, Argentina to San Antonio (Santiago), Chile

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Explore Beyond Event

Ports of call and details

From $15,898 per guest based on double occupancy

Veranda Suite, Explore Beyond Event

Taxes & fees included

Veranda Suite
$15,898
Penthouse Suite
$22,998
Panorama Penthouse Suite
$24,608
Owner's Suite and Above
$27,998
Request this sailing

Seabourn Pursuit · South America

34-Day Chilean Fjords, Easter & Pitcairn Islands

Mar 23 to Apr 26, 2027 · 34 nights

Buenos Aires, Argentina to Papeete, French Polynesia

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $29,598 per guest based on double occupancy

Veranda Suite, Seabourn Combo Savings

Taxes & fees included

Veranda Suite
$29,598
Panorama Penthouse Suite
$47,183
Owner's Suite and Above
$62,998
Penthouse Suite
Request this sailing

Oosterdam · Panama Canal

16-Day Inca & Panama Canal Discovery: Lima Overnight

Mar 24 to Apr 9, 2027 · 16 nights

San Antonio (Santiago), Chile to Fort Lauderdale, Florida, US

  • Drink package
  • Wi-Fi
  • Specialty dining
  • Shore excursions

Offers: Have It All - Our Premium Cruise Package

Ports of call and details

From $3,339 per person, double occupancy

Inside, Have It All - Our Premium Cruise Package

Taxes & fees included

Inside
$3,339
Ocean View
$3,539
Verandah
$5,039
Signature Suite
$5,839
Neptune Suite
$14,364
Request this sailing

Seabourn Pursuit · South America

19-Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers

Apr 7 to Apr 26, 2027 · 19 nights

San Antonio (Santiago), Chile to Papeete, French Polynesia

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Explore Beyond Event

Ports of call and details

From $17,298 per guest based on double occupancy

Veranda Suite, Explore Beyond Event

Taxes & fees included

Veranda Suite
$17,298
Penthouse Suite
$25,998
Panorama Penthouse Suite
$27,818
Owner's Suite and Above
$50,738
Request this sailing

Seabourn Pursuit · Australia & New Zealand

64-Day Kimberley Expedition & Islands Of The Pacific

Aug 16 to Oct 18, 2027 · 64 nights

Broome, Western Australia, Australia to San Antonio (Santiago), Chile

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $75,598 per guest based on double occupancy

Veranda Suite, Seabourn Combo Savings

Taxes & fees included

Veranda Suite
$75,598
Penthouse Suite
Panorama Penthouse Suite
Owner's Suite and Above
Request this sailing

Seabourn Pursuit · Australia & New Zealand

54-Day Indonesia, Papua New Guinea & Islands Of The Pacific

Aug 26 to Oct 18, 2027 · 54 nights

Darwin, Australia to San Antonio (Santiago), Chile

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $59,398 per guest based on double occupancy

Veranda Suite, Seabourn Combo Savings

Taxes & fees included

Veranda Suite
$59,398
Penthouse Suite
Panorama Penthouse Suite
Owner's Suite and Above
Request this sailing

Seabourn Pursuit · South America

72-Day Papua New Guinea, Indonesia, Patagonia & Antarctica

Aug 26 to Nov 5, 2027 · 71 nights

Darwin, Australia to Ushuaia, Argentina

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $78,798 per guest based on double occupancy

Veranda Suite, Seabourn Combo Savings

Taxes & fees included

Veranda Suite
$78,798
Penthouse Suite
Panorama Penthouse Suite
Owner's Suite and Above
Request this sailing

Seabourn Pursuit · Australia & New Zealand

32-Day Lost Islands Of Chile & Tracing Fiji's History

Sep 17 to Oct 18, 2027 · 32 nights

Lautoka, Fiji to San Antonio (Santiago), Chile

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $30,598 per guest based on double occupancy

Veranda Suite, Seabourn Combo Savings

Taxes & fees included

Veranda Suite
$30,598
Panorama Penthouse Suite
$53,498
Penthouse Suite
Owner's Suite and Above
Request this sailing

Seabourn Pursuit · Australia & New Zealand

50-Day Fiji To The Chilean Coast & Antarctica

Sep 17 to Nov 5, 2027 · 49 nights

Lautoka, Fiji to Ushuaia, Argentina

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $49,998 per guest based on double occupancy

Veranda Suite, Seabourn Combo Savings

Taxes & fees included

Veranda Suite
$49,998
Penthouse Suite
Panorama Penthouse Suite
Owner's Suite and Above
Request this sailing

Seabourn Pursuit · South America

19-Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers

Sep 29 to Oct 18, 2027 · 19 nights

Papeete, French Polynesia to San Antonio (Santiago), Chile

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Explore Beyond Event

Ports of call and details

From $19,168 per guest based on double occupancy

Veranda Suite, Explore Beyond Event

Taxes & fees included

Veranda Suite
$19,168
Penthouse Suite
$29,998
Panorama Penthouse Suite
$32,098
Owner's Suite and Above
$33,998
Request this sailing

Seabourn Pursuit · South America

37-Day South Pacific Explorer & Antarctica

Sep 29 to Nov 5, 2027 · 37 nights

Papeete, French Polynesia to Buenos Aires

  • Premium spirits and fine wines included
  • Up to $2,000 shipboard credit per suite
  • All dining venues included
  • 15% reduced deposit

Offers: Seabourn Combo Savings, Explore Beyond Event

Ports of call and details

From $35,598 per guest based on double occupancy

Veranda Suite, Seabourn Combo Savings

Taxes & fees included

Veranda Suite
$35,598
Panorama Penthouse Suite
$55,853
Owner's Suite and Above
$61,198
Penthouse Suite
Request this sailing

Nieuw Amsterdam · South America

26-Day Inca Coast: Mexico & Latin America Legendary Voyage

Oct 7 to Nov 2, 2027 · 26 nights

Vancouver, B.C., CA to San Antonio (Santiago), Chile

  • Elite Beverage Package upgrade
  • Premium Wi-Fi upgrade
  • Prepaid crew appreciation
  • Specialty dining
  • +1 more

Offers: Have It All Early Booking Bonus, Legendary Voyages: 25 – 59 Days

Ports of call and details

From $5,229 per person, double occupancy

Inside, Have It All Early Booking Bonus

Taxes & fees included

Inside
$5,229
Ocean View
$5,529
Verandah
$6,829
Signature Suite
$9,729
Neptune Suite
$12,229
Request this sailing

Nieuw Amsterdam · South America

41-Day Inca Coast Discovery Collectors' Voyage

Oct 7 to Nov 17, 2027 · 41 nights

Vancouver, B.C., CA to Buenos Aires, Argentina

  • Elite Beverage Package upgrade
  • Premium Wi-Fi upgrade
  • Prepaid crew appreciation
  • Specialty dining
  • +1 more

Offers: Have It All Early Booking Bonus

Ports of call and details

From $7,764 per person, double occupancy

Inside, Have It All Early Booking Bonus

Taxes & fees included

Inside
$7,764
Ocean View
$8,184
Verandah
$9,974
Signature Suite
$13,714
Neptune Suite
$17,024
Request this sailing

Nieuw Amsterdam · South America

21-Day Inca Coast Discovery Segment

Oct 12 to Nov 2, 2027 · 21 nights

San Diego, California, US to San Antonio (Santiago), Chile

  • Elite Beverage Package upgrade
  • Premium Wi-Fi upgrade
  • Prepaid crew appreciation
  • Specialty dining
  • +1 more

Offers: Have It All Early Booking Bonus

Ports of call and details

From $4,429 per person, double occupancy

Inside, Have It All Early Booking Bonus

Taxes & fees included

Inside
$4,429
Ocean View
$4,659
Verandah
$5,789
Signature Suite
$8,639
Neptune Suite
$10,939
Request this sailing

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Fares are per person, double occupancy.